[China Pharmaceutical Network Technology News] People have long discovered a compound called nicotinamide mononucleotide (NMN), which can delay the aging process of mice and prolong their life. So, does NMN have the same effect on the life of the human body? To this end, researchers at Washington University in St. Louis and Keio University in Japan conducted clinical trials.
Researchers at Washington University in St. Louis and Keio University in Japan are currently planning a clinical trial that will test the efficacy and safety of this compound, NMN, in humans. The plan will begin next month, with about 10 healthy people being injected with NMN, and scientists will see if it can improve the physical functioning of these participants and help them avoid the effects of aging. If it is useful, then it will be the first real anti-aging intervention available in the market.
NMN is an organic molecule, or a nucleotide, which is found in many human nutrient sources, including milk. Previous studies have shown that its principle of delaying the aging process is that it activates deacetylases in the body, and the function of such proteins diminishes as the body ages.
A study by Shinichiro Imai of the University of Washington showed that NMN is able to activate genes responsible for the synthesis of deacetylases. In one experiment, the researchers fed mice with NMN-rich foods. These stable NMN-infected mice have improved their physical function (such as metabolism and vision) due to age. In another experiment, NMN improved glucose intolerance in mice and improved their lipid levels. For mice, NMN is like elixir, but we still don't know if it has the same effect on humans.
Scientists have enough reason to believe that NMN can't do the same for humans. Experiments with mice, especially those related to aging, do not have too good results when transferred to humans. The role of NMN in humans cannot be as good as that of mice. After all, the life of plasticity of small mice is very strong.
This means that NMN has a positive impact on human physiology, and this effect can be measured intuitively. Even though NMN does not affect humans as much as humans, this compound can still be used to improve human health.
Researchers at Washington University in St. Louis and Keio University in Japan are currently planning a clinical trial that will test the efficacy and safety of this compound, NMN, in humans. The plan will begin next month, with about 10 healthy people being injected with NMN, and scientists will see if it can improve the physical functioning of these participants and help them avoid the effects of aging. If it is useful, then it will be the first real anti-aging intervention available in the market.
NMN is an organic molecule, or a nucleotide, which is found in many human nutrient sources, including milk. Previous studies have shown that its principle of delaying the aging process is that it activates deacetylases in the body, and the function of such proteins diminishes as the body ages.
A study by Shinichiro Imai of the University of Washington showed that NMN is able to activate genes responsible for the synthesis of deacetylases. In one experiment, the researchers fed mice with NMN-rich foods. These stable NMN-infected mice have improved their physical function (such as metabolism and vision) due to age. In another experiment, NMN improved glucose intolerance in mice and improved their lipid levels. For mice, NMN is like elixir, but we still don't know if it has the same effect on humans.
Scientists have enough reason to believe that NMN can't do the same for humans. Experiments with mice, especially those related to aging, do not have too good results when transferred to humans. The role of NMN in humans cannot be as good as that of mice. After all, the life of plasticity of small mice is very strong.
This means that NMN has a positive impact on human physiology, and this effect can be measured intuitively. Even though NMN does not affect humans as much as humans, this compound can still be used to improve human health.
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