toxicity
Leletoside has an inhibitory effect on the central nervous system in rabbits and has an antispasmodic effect on mice induced by shock. The LD50 is 65 mg/kg.
The king of Ge was once included in the “Chinese Pharmacopoeia†(1977 edition), and was not re-recovered due to the strong side effects of the Chinese medicine. There have been reports of related toxicities. In the future, the toxic components and their toxicological mechanisms should be studied in-depth and systematically to provide basis for clinical safety and rational drug use.
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