Australia develops new drugs against intestinal "super bacteria"

Medical Network January 23, Australia Flinders University has announced that the school's researchers have developed a new type of antibiotics, animal experiments show that it can effectively inhibit a drug-resistant intestinal "super bacteria."

Bacteria "resist" antibiotics in various forms to escape the danger of being eliminated. This resistance is called "bacterial resistance." Superbugs are bacteria that are resistant to a variety of antibiotics, and patients lack effective treatments after infecting superbugs. According to the World Health Organization, about 700,000 people worldwide die from drug-resistant infections such as super bacteria.

"C. difficile" is a bacterium that causes infection of the large intestine. It has gradually developed resistance to traditional antibiotics and is therefore a "superbug" that is common in people who take antibiotics for a long time. The toxins secreted by this bacteria can seriously damage the intestines and threaten the lives of patients. The Flinders University research team reported in a new issue of the British Science Report that they developed a new antibiotic called Ramizol that was injected into the deadly dose of C. difficile. After the hamsters in the body, it was found that a large part of the hamsters survived.

In another study evaluating drug safety, the researchers injected high doses of Ramizol into 48 rats for 14 consecutive days. The results showed that no rats had serious side effects or weight changes.

The researchers say this suggests that Ramizol is a well tolerated antibiotic for animals. In addition, Ramizol has good oxidation resistance, high chemical stability, etc., and has low manufacturing cost and is expected to be applied to humans.