Innovative progress in in vitro fertilization technology: first realization of fertilization in women

Release date: 2015-12-16

According to the British Daily Mail, recent in vitro fertilization (IVF) technology has achieved a breakthrough, the first to achieve fertilization in women, which may mark the end of the "test tube baby" era. This technique means that the first stage of vital embryo development can be done in the natural environment of the uterus, not in the laboratory.

This technology will be provided to couples who cannot naturally conceive. The doctor injects a device containing sperm and eggs smaller than the matchstick into the woman and removes it after 24 hours. Then evaluates whether the resulting embryo is healthy enough and then replants. Into achieve successful pregnancy.

Fertility experts say this will bring important psychological effects to women, because they are more involved in the child's birth from a physiological perspective. Doctors believe that this technology will also greatly increase the success rate of IVF and promote the long-term health of children.

This technology has been successfully applied in some European clinics. It was officially approved by the Fertility Authority Human Fertilisation and Embryology Authority (HEFA) in September this year. Next year's New Year's headquarters at the Southampton University Hospital's Complete Fertility Clinic will provide this technology, which is a few hundred pounds more expensive than the standard IVF price (3,800 pounds, about 36,608 yuan).

Nicholas Macklon, director of the clinic and professor of obstetrics and gynaecology at Southampton University, said: "The advantage of this technique is that early embryos will be exposed to the same natural chemical environment as natural fertility. We know that IVF infants are slightly different. - Their births are more important. Although this is not important for early survival, it is closely related to the long-term health of children."

“The growing evidence suggests that this is related to the medium we use in the laboratory, so if we can keep IVF in the womb for as long as possible, then these babies will not only benefit from all the mothers. It also avoids exposure to synthetic environments during the sensitive stages of early development."

During the IVF process, the eggs are removed from the female ovaries and fertilized with the sperm in a laboratory environment. Six days later, the fertilized embryo was reinjected into the female uterus for development and growth. The standard IVF involves six main stages: first, the female menstrual cycle is inhibited by drugs, and then other drugs are used to stimulate the ovaries to produce more eggs than usual. Ultrasound scans detect the development of the egg and then use further medications to help them mature.

In order to "acquire" the egg, the doctor injects the needle through the vagina into the female ovary. Traditionally, the acquired eggs are mixed with the sperm in a "test tube" - that is, a laboratory culture dish - for a few days to fertilize the two, and then the fertilized eggs are injected back into the female uterus.

The latest in vitro fertilization process involves mixing sperm and eggs and placing them on a 1 cm long 1 mm wide Anecova AneVivo device that can be painlessly injected into women without anesthesia. The process of fertilization has already taken place in the process of women returning home from the clinic.

Laila Lampino, 39, one of the first patients in Europe to use the device, said the experience of leaving her embryos in the lab was "very frustrating." So after the failure of the standard IVF, she agreed to try the Anecova equipment provided by the Clinique des Grangettes private hospital in Geneva, Switzerland. In 2010 she successfully gave birth to her daughter.

Blue Pino said: "My instinct tells me that this is the right solution. As a mother, the baby embryos in the body allow me to play an active role in the early developmental stages of the child. When we get home, I am The husband put his hand on my stomach and said, 'This moment is not in the lab, but in your body.' This is a wonderful feeling. We are really happy to finally have a baby."

Last month, the HFEA said at a meeting that there is no evidence yet that the technology is not safe. However, it warned that there is currently no evidence that it is more effective than the standard IVF, and it may "add unnecessary overhead to the patient."

Source: Sina Technology

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