American scientists have announced that research has shown that vitamin C supplementation may reduce the effectiveness of some anticancer drugs.
According to Agence France-Presse, the study was published in the October 1 issue of Cancer Research. Mark Hini, of the Sloan-Kettering Cancer Institute in New York, explained: "Supplement of vitamin C may reduce the ability of patients to cope with anti-cancer treatment."
Hini and his team of researchers tested a variety of chemotherapeutic drugs in cancer cells in the laboratory, some of which were pretreated with vitamin C. As a result, it was found that the rate of destruction of the anticancer drug against the cells pretreated with vitamin C was 30% to 70% lower than that of the untreated one.
The researchers implanted these cancer cells into mice and found that mice implanted with cancer cells pretreated with vitamin C grew faster in the body.
Researchers believe that certain drugs used in chemotherapy produce free radicals that block oxygen molecules, which can cause disruptive reactions with other molecules and cause cell death. But vitamin C seems to offset the damaging effects of free radicals on cancer cell mitochondria, making it viable despite chemotherapy. The issue of vitamin C supplementation during anti-cancer treatment has long been debated. Some studies have shown that vitamin C is an antioxidant that may be beneficial to cancer patients.
According to Agence France-Presse, the study was published in the October 1 issue of Cancer Research. Mark Hini, of the Sloan-Kettering Cancer Institute in New York, explained: "Supplement of vitamin C may reduce the ability of patients to cope with anti-cancer treatment."
Hini and his team of researchers tested a variety of chemotherapeutic drugs in cancer cells in the laboratory, some of which were pretreated with vitamin C. As a result, it was found that the rate of destruction of the anticancer drug against the cells pretreated with vitamin C was 30% to 70% lower than that of the untreated one.
The researchers implanted these cancer cells into mice and found that mice implanted with cancer cells pretreated with vitamin C grew faster in the body.
Researchers believe that certain drugs used in chemotherapy produce free radicals that block oxygen molecules, which can cause disruptive reactions with other molecules and cause cell death. But vitamin C seems to offset the damaging effects of free radicals on cancer cell mitochondria, making it viable despite chemotherapy. The issue of vitamin C supplementation during anti-cancer treatment has long been debated. Some studies have shown that vitamin C is an antioxidant that may be beneficial to cancer patients.
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