Medicinal material powder + accessories → mold release → molding → cover surface → drying → selection of pills → coating → lighting → quality inspection → packaging
Unless otherwise specified, usually the drug is crushed through the No. 6 sieve.
1. Starting the mold: the operation of preparing the basic mother core of the pellet, and selecting a powder with suitable viscosity.
Powder direct-release method: spray a small amount of water in the pan-pill pot to wet, sprinkle a small amount of powder, turn the pan-pill pot, brush the attached powder, then spray water, dust, repeat the cycle, the powder gradually enlarges to about the diameter In the case of a 1 mm ball, the particles between the first and second sieves are sieved to form a pellet.
Wet powder granulation model: the powder is mixed with water to make it into a group, shake it to the degree, and the above soft material passes through the No. 2 sieve, into the panball pot, after rotation, rolling, rubbing, into Spherical, take out the sieve, etc., that is, the pellet mold.
It can also be used to coat the granulator, the speed is fast, the pellet is round and uniform, but the pellet is loose.
2. Molding: The evenly screened pellets are gradually increased to near the finished product.
The method is the same as the mold-taking, repeatedly adding water to the mold, moistening, dusting, rounding, screening
Can be layered according to the nature of the drug, masking bad smell, avoiding incompatibility
Minerals containing cinnabar, sulfur and other minerals avoid using metal panballs to avoid discoloration or toxic substances
Control the particle size and roundness of the pellets, and the firmness is limited to acceptable dissolution.
Mixed granules: Mix the powder with water to make a mixture of d≈1.32-1.33 (stir well before use), and filter the uniform pellets in the panball pot and rotate them in the opposite direction to spray the mixture into the pellets. The cycle is fed in a less-to-many manner. Add appropriate powder to prevent sticking and sticking.
3. Cover: The pellets that have been enlarged, qualified, and screened continue to be surface treated in the panball pot. To meet the requirements of the size of the finished product, the surface is smooth, compact, and uniform in color.
Dry powder cover: for fully wetted pellets
Clear water cover: For dry surface pellets, it should be dried quickly to prevent color changes.
Grouting cover: The clear paste is made of powdered medicine or waste pellets, and the operation is covered with water.
4. Drying: Due to the large water content, the panicles are prone to mold, so the pellets should be dried in time after the cover, so that the water content is controlled within 9%.
Generally, the drying temperature is 80 ° C or less.
If the pill contains aromatic volatile components or components that are easily decomposed by heat, the drying temperature should not exceed 60 ° C. It can be boiled and dried in a fluidized bed. The temperature can be controlled at 75-80 ° C. The drying is fast and the moisture can reach 2.5% or less.
Microwave drying can also be used, the speed is faster, the internal and external dry humidity is uniform, the puffing effect is favorable for dissolution, and sterilization is provided.
5. Selecting pills: to ensure that the pellets are round and uniform in size, generally through the roller screen and the pellet detector.
6. Optional coating
If you want to know more about Chinese medicine water pill machine , please log in to our company: or direct pharmaceutical technology department : consultation, our factory will provide you with more professional services!
1. Function: It can produce water pill and pelletized food coating, drying, etc.
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