Release date: 2007-05-23
The study found that vitamins and magnesium mixture can prevent hearing loss According to foreign media reports, scientists found that vitamins and magnesium mixture can prevent hearing loss caused by noise damage. Soldiers in deafening battles are often reluctant to wear protective gear like earplugs that can make them less exposed to danger. But what if you eat a piece of candy every day to prevent such potential hearing damage? Researchers at the University of Michigan found in a new animal study that a high-dose combination of vitamin A, vitamin C, vitamin E, and magnesium was taken one hour before noise exposure and continued for five days. The permanent hearing loss caused by noise is very effective. Dr. Joseph Miller, a professor of physiology, said that clinical trials of a tablet or food that protects hearing can begin shortly after, and if the clinical trial is successful, such a product can be available in two years. Joseph Miller is the lead author of the study, which was published online in the journal Free Radical Biology and Medicine. Miller is a professor of otolaryngology at the University of Michigan Medical School. The available evidence suggests that such nutrients can effectively suppress the excessive activity of free radicals, which is the main cause of hearing loss after being damaged by noise - damage to the inner ear. Miller said, "These agents have been used for many years, but they have not been used to treat hearing loss. We have found that they are safe, so this makes it possible to advance clinical trials, and we are sure that it will not cause any damage." This dosage form used is based on previous animal studies. Animal studies have shown that a single antioxidant vitamin has a slight effect on preventing hearing loss. At the same time, previous studies have shown that magnesium taken for many days before exposure to noise can provide relatively relatively small protection. In a study at the University of Michigan, the researchers looked at four groups of guinea pigs, each given antioxidant vitamin A, vitamin C and vitamin E, magnesium alone, vitamin ACE or placebo. One hour after taking the drug, the animals were exposed to noise of 120 decibels of sound intensity for five consecutive days, once a day. The group of guinea pigs taking vitamin A, vitamin C and vitamin E and magnesium mixture were significantly less affected by noise due to noise. Researcher at the University of Michigan's Kresger Hearing Institute, co-author of the paper, explains that vitamin A, vitamin C, vitamin E and magnesium work synergistically to prevent cell damage. According to the researchers' findings, taking drugs in advance reduces the amount of active substances called free radicals, while reducing neurotoxic toxicity or reducing damage to auditory neurons due to excessive stimulation. In the past decade, scientists have found that noise causes hearing loss in part because the mitochondria of the ear produce a lot of harmful free radicals and react to harsh sounds. The vitamins and magnesium used in this study are widely used food supplements and are not new drugs, so they do not require extensive safety testing as new drugs require before clinical trials. According to the medical institution and the federal nutrition policy, the dose for human testing will be within safe limits. Miller said, "Ultimately, we envisage that our soldiers will eat this nutrient together with the food, it will give them enough daily protection." Similar food with other ingredients has been given to the soldiers, Help them withstand the heat and other environments of the war zone. “Others may also benefit from taking this pill or nutritive candy bar, such as before entering a noisy environment, or participating in activities like the National Auto Racing Association car or rock concert, and even using it,†said Pryle. iPod or other music player. Based on previous studies of other antioxidants, we believe that these micronutrient combinations are effective even in a noisy environment.†The study also proposed an "after the scene" therapy, which may Minimize hearing damage for soldiers, musicians, pilots, construction workers, and others. According to the National Association of Deafness and Communication Disorders, approximately 30 million Americans are often at work and at home at hazardous noise levels. Tracked snowmobiles, the use of machines such as fan blades, lawn mowers and power tools, as well as participating concerts, often put people at dangerous levels of noise. Noise levels above 85 decibels can damage your hearing. About 28 million Americans have experienced hearing loss to some extent. About one-third of them have hearing impairments that are at least partially related to noise. The University of Michigan study has also added strength to the research work of many other research centers to explore how these nutrients are used in other diseases. "A similar combination has been very effective in preventing macular degeneration," said Pryle. "Many of these agents have been used in Alzheimer's and Parkinson's syndrome, stroke and other neurodegeneration." ——Shanghai Medical Device Industry Association
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