Talking about the Application of Vacuum Feeding Equipment in Pharmaceutical and Food Powder Transportation System

For a long time, in the production of solid preparations in the pharmaceutical industry, the problem of powder material transportation between production stages has become an important issue in improving production processes and improving product quality. In China's solid preparation enterprises, the production methods of artificial ingredients and manual feeding are common. For example, the typical production process of a manufacturer from one-step granulation drying to total mixing is shown in the figure:

In this process, the contact between the person and the drug is three times, and the material can be used in the next step through three intermediate containers, which not only increases the labor intensity of the worker, but also makes the process cumbersome, and more importantly, it increases. The possibility of cross-contamination of materials, at the same time, in the process of transport, may cause a large amount of dust, pollute the environment, affecting the health of the operator. Some materials are also flammable, explosive, toxic, harmful and other special properties, which is even more unsuitable for this method. This is also the case in the process of tableting and capsule filling, and most domestic manufacturers still use manual feeding. The ideal conveying method of Zui should be: to minimize the direct contact between people and materials, so that the material transportation can be completed in a closed environment, which can save labor, reduce costs, avoid cross-contamination, and improve solid preparations. The degree of automation of the production process.

Beijing Tianli Process Technology Co., Ltd. has many years of experience in the pharmaceutical industry. For the current methods of conveying powder materials in solid preparations in China, we mainly summarize the following types: positive pressure conveying, negative pressure conveying and hoist feeding. . These forms can basically meet the requirements of reducing labor intensity, reducing dust and protecting materials from environmental pollution. However, these forms have their own advantages and disadvantages. Below we briefly introduce the advantages and disadvantages of these methods: positive pressure The transportation is mainly divided into two forms: high pressure conveying and low pressure conveying. The conveying capacity of high pressure conveying is relatively large and the conveying distance is long, but the equipment is complicated, bulky, difficult to install, and the price of parts is relatively high. The high pressure conveying is to the pipeline and materials. There is a large amount of wear and there is a possibility of leakage. The low-pressure conveying system has relatively little wear on the material, but its conveying capacity is limited, and there is also the possibility of leakage. The way of hoist feeding is currently used by pharmaceutical manufacturers in a more expensive way, but its large footprint, high energy consumption, and complicated operation control are not the first choice for material conveying.

Negative pressure conveying, that is, vacuum conveying, it uses a fully enclosed conveying system to transport bulk materials (powder, granules), which completely eliminates environmental pollution caused by material leakage and damage to the operator's body, and The surrounding environment is contaminated with materials. It is the development direction of powder material transportation in recent years. The vacuum source of the vacuum feeder has various forms, such as a vacuum generator, a vacuum pump, a Roots blower, and the like. The vacuum generator has the advantages of small size, light weight and easy installation. It can be applied in the clean workshop. It uses jet technology to make the vacuum generator generate high vacuum under the action of compressed air to realize the material transportation. No mechanical vacuum pump is needed. There are no lubricating components and almost no moving parts, which is fully compliant with GMP requirements. The pneumatic vacuum conveying system is mainly used for conveying and feeding solid materials such as powder and granules in the pharmaceutical and food industries. It can be used together with main process equipment such as mixer, granulator, tablet press, coating machine, capsule filling machine, packaging machine; with its continuous application in China, it will definitely optimize production in this field in China. The process has effectively reduced cross-contamination and dust, and has a positive effect on improving the quality of pharmaceutical production.

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