Release date: 2015-06-01
Memory can be “lost†by forgetting but not “disappearingâ€. New research has found that memory can be activated by light to activate brain cells.
Researchers can do this by using optogenetic techniques to control elevated neurons in the brain in mice.
The study brings hope to those who suffer from memory loss due to brain damage. According to MIT professor Susumu Tonegawa, this answers the academic debate about the nature of amnesia.
For years, researchers have been arguing whether specific brain cell damage caused by trauma, stress, and diseases such as Alzheimer's disease is retrograde forgetfulness. This means that memory cannot be stored, or that memory is blocked for some reason, preventing it from being retrieved.
Most researchers prefer storage theory, but Professor Tonegawa said that their research suggests that the theory that most people support may be wrong.
In the latest study, the researchers first trained mice with environmentally-related mild stimuli to give mice "freezing" behavior. After training, even if there is no stimulation, put the little uncle in the secret room will freeze.
Scientists genetically tag neuronal activation during memory formation in order to be able to retrieve memory in the future.
The researchers used chemicals to block some of the mice's memory-encoded enhanced synapses. When these mice are returned to the chamber, they will not be able to remember the stimuli and therefore will not be frozen.
The researchers then used optogenetic techniques to selectively activate sputum-labeled neurons during training. When the memory was activated again, the mice showed freezing behavior, which showed that they recovered their memories.
The researchers also said that this study separates the principle of memory storage from memory retrieval.
Original link: http://
Source: Kexun Medical Network
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