Medicinal value of Radix Isatidis

1, the role of anti-pathogenic microorganisms

Indigo root has inhibitory effects on various bacteria. Aqueous extracts have various degrees of inhibition on Bacillus subtilis, Staphylococcus aureus, Bacillus, Escherichia coli, Salmonella typhi, Paratyphoid bacillus, dysentery (Shiga, Freund's bacillus), enterobacteriaceae, etc.; acetone leaching solution also has Similar effect, and effective for hemolytic streptococcus (all agar plate method). The antibacterial activity against meningococci A is similar to that of garlic and honeysuckle. Influenza virus PR8 strain and Jingke 68-1 strain significantly inhibited. In the test tube, Radix has the effect of killing Leptospira.

2, the role of cardiovascular

Experiments show that the product can increase the perfused flow of isolated rabbit ears and rat lower limbs, improve mesenteric microcirculation in rabbits, reduce blood pressure in anesthetized rabbits, reduce capillary permeability, and reduce myocardial oxygen consumption in mice.

3, inhibit platelet aggregation

Radix is ​​a significant inhibitory effect on ADP-induced platelet aggregation in rabbits. Inhibitory activity of uridine, hypoxanthine, pyrimidine, salicylic acid, etc. on platelet aggregation induced by ATP in Radix Isatidis was also observed. The inhibition rate was 0.2% at a concentration of 0.21 mg/kg, and was 24.2%. %, 10.8% and 20%.

4, detoxification

It has been reported that dogs with Radix Isatidis, Coptis flour, and Veratrum alfalfa served together (2.0g/kg each), which could resolve the reed detoxification and reduce mortality; if they were used after being poisoned with veratrum, they would be ineffective; Or Coptis powder, the effect is not good.